Full-Spectrum Extracts vs. CBD Isolates

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     Here at HempCo:CBDriven Nutraceuticals we believe our full spectrum, whole plant extracted CBD is superior to many of the isolates showing up in the market today. This article goes into detail of why we use whole plant extracted CBD in our CBD Salves!

September 9, 2015 by

     Cannabidiol (CBD) has been the focus of many medical cannabis studies, and continues to prove itself as a powerful anti-inflammatory drug. What makes CBD even more desirable for some patients is that it does not cause the psychoactive effects associated with tetrahydrocannabinol (THC).

An extremely interesting study (Overcoming the Bell-Shaped Dose-Response of Cannabidiol by using Cannabis Extract Enriched in Cannabidiol) was just published out of the Lautenberg Center for General and Tumor Immunology in Jerusalem. The study examines the effectiveness of administering isolated cannabinoid extracts (a CBD-only formula) versus whole plant extracts (which contain the full range of the plant’s cannabinoid content).

     The Hadassah Medical School at the Hebrew University of Jerusalem sought to compare the effectiveness of a completely purified CBD extract versus a full-spectrum extract of cannabis flowers containing large quantities of CBD. The conclusion of the study was that the whole plant extract, which contained a large percentage of CBD but also contained traces of the other cannabinoids, proved far more effective than CBD-only solutions in alleviating inflammation and pain sensation. The study demonstrated that a whole plant extract, containing the entire range of cannabinoids present in raw cannabis, will continue to provide relief for inflammation as the dose is increased. When supplied as an isolated cannabinoid extract, CBD on its own yielded a bell-curve of effectiveness, which is not desirable for medical treatments seeking effective relief that corresponds with the dosage.

Conclusion: Cannabinoid Synergy More Effective Against Swelling

Cannabis studies continue to legitimize the medical relevance of the different cannabinoids. However, this study shows the importance of treating ailments using the full range of cannabinoids available. Gallily, Yekhtim, and Hanus, the authors of this study from the Hebrew University of Jerusalem, conclude that cannabis extracts, specifically cannabidiol, can be more effective for anti-inflammation treatment than the familiar commercial drugs on pharmacy shelves.

This study is important because it confirms the importance of cannabis as both medication and a natural plant. Many pharmaceutical companies have been trying to create synthetic derivatives of the different cannabinoids, but it turns out that the entirety of the raw cannabis plant is more beneficial than a single isolated cannabinoid. The results of this study are extremely promising for the future of cannabis science and medicine.

Calming Calendula

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     marigold-555811_1920Here at HempCo we spend a lot of time contemplating what ingredients we need to add to perfect our CBD salves, which herb would be best, etc. The one medicinal herb we added without a question was Calendula officinalis.

     Calendula officinalis, despite its common name Pot Marigold, should not be confused with the similar looking true marigolds (Tagetes), found in many neighborhood gardens. The name Calendula comes from the Latin kalendae, for “first day of the month” which may refer to the fact that the plant can be found blooming at the beginning of most months.

     Calendula’s brightly colored flowers’ cultivation dates back to at least 1885-even before recorded cultivation Calendula’s medicinal properties were commonly noted. British herbalists John Gerard (1545-1612) and Nicholas Culpepper (1616-1654) both mention “marigold.” In 19th century America, many physicians used calendula externally for superficial burns, bruises, and wounds. In the 20th century, British author, Maud Grieve, states that it is primarily a local (topical) remedy and that applying the petals to insect stings will reduce pain and swelling. She also recommended a lotion made of the flowers for sprains and wounds. Sounds like Maud Grieve would support Calendula in our CBD salves.

             Many modern herbalists choose Calendula for bruises, sprains, wounds, chapped/dry skin and any type of skin inflammation, such as rashes, bed sores, leg ulcers, boils, etc. Calendula can be used for all skin types, especially for sensitive skin. Calendula has been proven to be antimicrobial, anti-inflammatory, wound-healing, anti-tumor, mild antispasmodic and anti-fungal.  Even the German Commission has approved the use of Calendula externally for poor-healing wounds and foot ulcers. Calendula is so good at healing wounds many recommend to not apply to oozing wounds, because it can heal so quickly it can seal in the pus. So as long as you keep that in mind, Calendula will never steer you wrong! No wonder it is such a healing ingredient in our CBD salves.

Healing Powers of Helichrysum

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     Besides hemp-derived CBD and Lavender essential oil (which we went into detail in last month’s newsletter), our CBD Skin Salve contains Helichrysum essential oil. Helichrysum is an incredible medicinal herb, but here at HempCo we found out that African Helichrysum is one of very few plants, other than cannabis and hemp, that contains cannabinoids, specifically CBG, and now we couldn’t be more excited about this plant’s healing possibilities!
Helichrysum, Helichrysum italicum, is a non-toxic, non-irritant, strongly aromatic herb native to the Mediterranean. The name “Helichrysum” is derived from the Greek word ‘helios’ meaning sun and “chrysos” meaning gold, referring to the brightly colored daisy-like flowers. Helichrysum Essential Oil is an important ingredient in our CBD Skin Salve. This essential oil was used in herbal health practices in ancient Greece and is obtained by steam distillation of the flowerheads.

     Leonardo Santini is considered the father of modern studies on Helichrysum. In the1930s, Santini began to administer a decoction (plant material in boiling water) and syrup of the Helichrysum plant for patients who were suffering from bronchitis and asthmatic cough. Not only did the patient’s respiratory conditions improve, but also other unrelated diseases from which they were suffering, particularly psoriasis and arthritis. After more and more success in using Helichrysum in the treatment for psoriasis, Santini confirmed the beneficial effects in two independent clinical studies carried out in the 1950s. In the 1995 study, all the participants’ psoriasis improved after only three weeks, leading to a great support for Helichrysum for psoriasis treatment. When it came to arthritis, Santini determined that the clinical activity of Helichrysum was similar of that of cortisone! Few studies have been conducted since Santini, but many practitioners and herbalists here at HempCo, swear by Helichrysum for it’s skin saving/renewing properties.

         Also referred to as the Everlasting or Immortal Flower, Helichrysum is highly valued and sought after for its many benefits, mainly focusing on its restorative and anti-aging properties to the skin. In addition to psoriasis, Helichrysum is used for a variety of skin conditions, such as burns, scars, wounds, dermatitis and eczema. Helichrysum oil inhibits microbial growth and protects the body against a long list of microbial infections, meaning it can be safely applied to wounds and any other open cores that could become infected. Helichrysum makes the skin smooth and, soft, and helps it retain moisture, as well as preventing dehydration and cracking of the skin. Many use Helichrysum to reduce the appearance of blemishes, wrinkles and to promote a youthful complexion.

         Another reason why Helichrysum is named the anti-aging flower is due to its anti-inflammatory properties. Helichrysum interrupts pro-inflammatory signalling and has a very similar anti-inflammatory profile to curcumin, an active ingredient in the powerful anti-inflammatory turmeric. In addition to the compound arzanol, there are a number of other bioactive compounds, including flavonoids, acetophenones and phloroglucinols, that exist in Helichrysum that complement its anti-inflammatory activity.

       Helichrysum italicum is a medicinal plant with promising pharmacological activities. However, most of the traditionally claimed applications we reviewed are not yet scientifically proven. Clinical trials are needed to further confirm this data and promote Helichrysum as an important ingredient in the treatment of several diseases. Here at HempCo we are excited for what the future holds for Helichrysum and cherish its healing properties!

    Learn what other ingredients are in our salves: www.cbdriven.com/shop

Treat Your Skin to Lavender

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    Besides hemp-derived CBD, both our CBD Skin Salve and CBD Pain Salve contain Lavender essential oil. Lavender essential oil is created through steam distillation of the fresh flowers. In addition to the essential oil, our CBD Skin Salve contains lavender-infused coconut and olive oil. So as you can tell we are pretty pumped here at HempCo– not only about CBD, but also about the healing benefits of lavender flowers.

    Lavender is a highly aromatic wood shrub with beautiful violet/blue flowers. This potent healing plant is native to the Mediterranean, but has become a very popular addition to many gardens here in the United States. When looking at vitalist energetics, Lavender is a warm and dry herb, which acts as both a relaxant and a stimulant to our systems. Lavender is very complex, containing many different chemical constituents, all contributing to the oil’s therapeutic effects.

    Lavender’s healing properties were first discovered by French scientist, Rene Gattefosse. He found that Lavender had the ability to promote tissue regeneration and speed wound healing after he severely burned his arm in a lab accident. Clinically speaking, Lavender is considered a sedative, anti-depressant, anti-inflammatory, anti-microbial and rubefacient (causes your skin to turn red because it increases circulation).

    Lavender is famous for being known as an all-purpose oil for skin care. Non-irritating to all skin types, Lavender is used for accelerating  healing of wounds, scars, burns, bruises, insect bites and stings, and soothing skin diseases, such as abscesses, acne, allergies, boils, athlete’s foot, sores, ringworm, psoriasis, dermatitis and eczema. Addition to skin care, Lavender is great for circulation, muscles and joints. We use in this essential oil in our CBD Pain Salve because it is great for muscle aches and pains, sprains and rheumatism. Another big component of Lavender essential oil is when added to a recipe, like both our CBD Skin Salve and CBD Pain Salve, it not only has its own strong medicinal qualities, but also strengthens the effects of the other oils in the mixture.

    Along with the physical medicinal attributes, many use Lavender for aromatherapy to help balance emotions, another reason why this herb/essential oil is a great addition to both our CBD Salves. The aromatic Lavender has been shown to relieve stress, tension, anxiety, nervousness, and depression, leading Lavender to have a calming, relaxing and balancing effect on us emotionally.

       Since Lavender has no contraindications and is healing/non-irritating to all skin types, it is a great addition to both our CBD Skin Salve and our CBD Pain Salve. Learn what other ingredients are in our salves: www.cbdriven.com/shop

Fibromyalgia & CBD

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          Fibromyalgia is a complex medical condition characterized by chronic widespread musculoskeletal pain, and a heightened and painful response to pressure, that has lasted for at least three months. Widespread pain refers to pain that occurs on both sides of one’s body, as well as above and below the waist. To make matters worse, this disorder’s pain is accompanied by chronic fatigue, as well as sleep, memory and mood issues. Many experience fatigue constantly, no matter how many hours they slept. This is often due to their sleep being disrupted by pain. Impaired ability to focus, pay attention and concentrate on mental tasks are some of the memory issues associated with fibromyalgia. Sadly, many people who have fibromyalgia also suffer from depression, headaches and pain/cramping in lower abdomen. This pain and lack of sleep can interfere with one’s ability to function properly at home and in the workplace.

     Unfortunately, the exact cause of fibromyalgia is still unknown. Symptoms sometimes begin after a physical trauma, surgery, infection or significant psychological stress. In other cases, symptoms gradually accumulate overtime, with no single triggering event. Researchers believe repeated nerve stimulation causes people’s  brains to change. This change involves an abnormal increase in levels of certain chemicals in the brain that signal pain (neurotransmitters). The brain’s pain receptors seem to develop a memory of the pain and become more sensitive, meaning they begin to overreact to pain signals.

     There is no cure for fibromyalgia, but there are a number of treatments. Alas, for the longest time there was not one treatment that was created solely for fibromyalgia. Pain relievers, both over the counter and prescription, are the main treatment. Antidepressants, like Duloxetine and Milnacripran, help ease the pain and fatigue associated with fibromyalgia, while Prozac helps promote sleep. Anti-seizure medications that are designed to treat epilepsy are also sometimes helpful in reducing the pain due to fibromyalgia. Pregabalin was the first drug approved by the FDA to treat fibromyalgia. However; Pregabalin has a very long list of side effects, some of which are: infection, headache, twitching, visual field loss, cognitive dysfunction, speech disturbance, accidental injury, tremor, drowsiness. These side effects for the treatment of fibromyalgia could be worse than the actual symptoms.

     Luckily, the therapeutic use of cannabis for different types of pain, including fibromyalgia, is currently being extensively investigated. As of now, there is little long-term clinical information on the effectiveness of cannabinoids in improving fibromyalgia symptoms, but this is changing rapidly. One study was conducted to describe the patterns of cannabis use, the associated benefits reported by patients with fibromyalgia, as well as the quality of doctorlife of fibromyalgia patients who consumed cannabis, versus fibromyalgia subjects who were not cannabis users. The conclusion of the study determined “the use of cannabis was associated with beneficial effects on some fibromyalgia symptoms.” All symptoms assessed showed statistically significant improvement, relief of pain, stiffness, relaxation and somnolence, following two hours of cannabis consumption.

        Overall, there is evidence that cannabinoids are safe and effective in improving sleep and providing pain relief in fibromyalgia patients and showed that the treatment is well tolerated. Like with every condition, we hope more and more research is conducted to show the relationship between cannabis, specifically cannabinoids, and the alleviation of the life consuming symptoms fibromyalgia patients endure.

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