THC vs. CBD

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What are the differences?

 

    The Cannabis plant (including both hemp and marijuana), has been a hot topic in recent years, as more and more states begin to decriminalize or even vote to legalize the cultivation of it. As a society we are all very familiar with THC, tetrahydrocannabinol, a main constituent in many marijuana plants, but many are not as familiar with the other important cannabinoids found in cannabis, one being CBD or Cannabidiol. CBD and THC are two main constituents found in the Cannabis plant, and both belong to a class of over 60 compounds known as cannabinoids. 

Hemp Plant     Throughout the years, we have seen many strains of marijuana grown with high levels of THC, while high CBD strains are very rare until recent times. The last couple of years, interest in CBD has grown tremendously, due mainly to its medicinal qualities, causing us to also see more and more high CBD strains.

    Even though CBD and THC are both in the same class of compounds (cannabinoids), there are several very important characteristics that differentiate the two.

Psychoactive Properties

    THC is a psychoactive ingredient in marijuana and will get you high, while CBD will not. In fact, research shows that CBD can actually counteract the psycho-activity of THC. CBD is a way for consumers to receive the medicinal benefits of Cannabid, without feeling “stoned.”

 

Receptors

    CBD has a greater affinity for CB2 receptors than CB1. THC has a greater affinity for CB1 receptors. Most of CBD’s therapeutic influence stems from its ability to break down anandamide (another cannabinoid) naturally produced in the body, often referred to as the bliss molecule. This keeps the natural cannabinoid active at higher concentrations for longer periods of time.

 

Legality

    Since our CBD is derived from high-CBD hemp extracts, it can be legally sold throughout the United States. Even though on a state level THC is becoming decriminalized more and more, and even legal in a few states, on a federal level, there are still strict laws set in place regarding marijuana.

Uses of CBD

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April, President of Product Development, applies HempCo’s CBD Pain Salve to her Market Assistant’s  aching neck at our booth at this year’s NoCo Hemp Expo.

CBD, or cannabidiol, has recently been receiving a lot of attention in the medical community, and for good reasons. There are numerous studies published that show the tremendous medical value CBD contains, unfortunately very few studies have been performed on humans, but this is about to change. 

 

When it comes to CBD, numerous studies show CBD positively effects neurological diseases, inflammatory illness and cancer. CBD is best for therapeutic treatment of neurodegenerative illness such as pediatric epilepsy. CBD can help prevent nerve damage due to alcohol poisoning. CBD appears to calm autonomic responses to stress like rapid heartbeat by engaging receptors that select serotonin to achieve a calming effect.

 

Cannabidiol’s therapeutic potential is based on its antipsychotic anxiolytic and antidepressant effects. CBD is able to reduce symptoms of acute paranoid schizophrenia as well as pharmaceuticals like amisulpride which, unlike CBD has, significant side effects. 

 

CBD has been shown to have clear and measurable therapeutic impact on inflammatory and anti-inflammatory regulation mechanisms such as inflammatory bowel disease, arthritis, periodontitis and atherosclerosis.

 

With regards to cancer, CBD is able to produce significant anti-cancer activity both in vitro and in vivo. Further, CBD has been shown to selectively produce oxidative stress in cancer cells,* thus producing apoptosis (cancer cell suicide) without impacting normal cells.  

 

These are just some of the many findings we are learning about how CBD can benefit our communities. 

 

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